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Humane Society of South Carolina
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Humane Society News

We now offer online Preventative options! Get your pet’s medications shipped right to your door.

Click here to order now!

*must be an existing client of the Humane Society SC

HSPCA Spay/Neuter Clinic offers vaccines and routine testing

Vaccinations and Testing is available
Monday through Thursday between the
hours of 8:30 AM and 11:30 AM.

 

Contact Us Now! Click Here

Success Stories


Here at the Humane Society we come across many innocent animals who are in need of special care. Many of these animals are neglected or turned in to be euthanized by the veterinarians. We love to share some of our success stories.

Read More >

Contact Information

The Humane Society South Carolina
405 Greenlawn Drive, Columbia, SC 29209

Email: [email protected]
803.783.1267 | Phone

Spay/neuter/vaccine Clinics are located at:

Columbia
405 Greenlawn Drive
Columbia, SC 29209
*Surgery Drop off is daily between 7:00 AM and 8:00 AM

Florence
815 Second Loop Rd
Florence, SC 29505
*Surgery Drop off is daily between 7:30 AM and 8:30 AM

Office Hours

Monday-Thursday – 8:30am-5:00pm
Friday-Sunday – Closed

Vaccine Hours at our clinic at 405 Greenlawn Drive

8:30am – 11:30am Monday – Thursday

Office closed from 12:30pm-1:30pm daily

© 2026 Humane Society of South Carolina.

Close Menu
  • About
    • Who We Are
    • MONTHLY SPECIALS
    • Employment Opportunities
    • CONTACT US
  • register
  • VOLUNTEER
  • SC Spay/Neuter Locations in SC
  • Spay/Neuter Services with Us
    • F.A.Q
    • Surgical Instructions
    • Services & Fees List
    • Make a Spay/Neuter/Vaccine Appointment
  • Other Services
    • Adoption Referral
    • Trap Neuter Vaccinate Return
    • NEWSLETTER
  • Cruelty
    • ANIMAL CRUELTY F.A.Q
    • GENERAL INFORMATION
    • Report Animal Cruelty
  • Events
    • Woofstock
    • EVENTS
  • Locations
  • DONATE
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