We now offer online Pharmacy options!

Ship your pet’s medications right to your door

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*must be an existing client of the Humane Society


The Humane Society for the Prevention of Cruelty to Animals (The Humane Society) is a 501c-3 charitable organization located in Columbia, South Carolina.

The Mission of the Humane Society is to end animal cruelty, neglect, and overpopulation by offering low cost spay and neuter surgery and assist in reports of animal cruelty.

In addition to our spay/neuter program and assistive services, we offer a program to help manage colonies of feral cats. We promote responsible feral cat colony management and offer humane traps and carriers for the public to use in order to spay/neuter feral colonies.

Learn about our monthly Feral Friday events


Click on the button above to schedule an appointment for spay/neuter surgery or for vaccines in our clinic. It is the fastest and easiest way to schedule. You can also send us an email at info@humanesc.org or call us at 803.783.1267.

Schedule NOW


Donate in Celebration of Life 

Let your pet’s memory live on by donating in their name to our Celebration of Life campaign. Celebrating the life of your pet with a tax deductible donation to the Humane Society will support us in our efforts in ending animal cruelty, neglect and overpopulation.